Cardiac Stem Cell Research
Results from a ground-breaking
Cedars-Sinai Heart Institute clinical trial show that an infusion of
cardiac stem cells helps damaged hearts regrow healthy muscle.
The first-in-man clinical trial, based on technologies and discoveries made by Eduardo Marbán, MD, PhD, and led by Raj Makkar, MD, explored the safety of harvesting, growing and giving patients their own cardiac stem cells to repair heart tissue injured by heart attack.
The
study’s findings, published in The Lancet, show that heart attack
patients who received stem cell treatment demonstrated a significant
reduction in the size of the scar left on the heart muscle; this is a
pioneering stem cell result, says Marban, who notes the study shows
actual regeneration of tissues. With support from the California
Institute for Regenerative Medicine, the Heart Institute team is now
planning future clinical trials to treat advanced heart disease patients
with stem cells.The first-in-man clinical trial, based on technologies and discoveries made by Eduardo Marbán, MD, PhD, and led by Raj Makkar, MD, explored the safety of harvesting, growing and giving patients their own cardiac stem cells to repair heart tissue injured by heart attack.
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